Dr. sc. Marina Šagud

Klinika za Psihijatriju

Medicinskog Fakulteta  Sveučilišta u Zagrebu , KBC Zagreb

Životopis

MarinaRođena sam u Zagrebu, gdje sam završila osnovnu školu i gimnaziju te diplomirala 1988. na Medicinskom fakultetu Sveučilišta u Zagrebu.

Nakon odrađenog pripravničkog staža 1989-1990, radila sam u farmaceutskoj kući „Pliva“ od 1991. do 1993. Od 1993 do 1997. sam bila specijalizant psihijatrije u Klinici za Psihijatriju, KBC Zagreb. Od 1997. sam specijalist psihijatar u Klinici za Psihijatriju, KBC Zagreb. Doktorsku disertaciju pod naslovom: Trombocitni serotonin, trombocitna MAO i serumski lipidi u dijagnostici i liječenju poremećaja raspoloženja, pod mentorstvom prof. dr. sc. Alme Mihaljević-Peleš obranila sam 2007.

Od 2008. sam viši asistent, a od 2012 docent, na katedri za psihijatriju i psihološku medicinu Medicinskog fakulteta sveučilišta u Zagrebu. Također sam tajnica i koordinator za e-učenje katedre za psihijatriju i psihološku medicinu Medicinskog fakulteta sveučilišta u Zagrebu. Od studenog 2011. sam voditelj odjela intenzivne njege Zavoda za afektivne poremećaje

Sudjelujem kao istraživač u kliničkim studijama, kao i u nekoliko Projekata Ministarstva znanosti u Klinici za psihijatriju KBC Zagreb i Institutu Ruđer Bošković.

Moj svakodnevni rad uključuje skrb za bolesnike na zatvorenom i otvorenom dijelu odjela za afektivne poremećaje, nastavu na dodiplomskom studiju medicinskog fakulteta sveučilišta u Zagrebu, diplomskom studiju sestrinstva, doktorskom studiju biomedicina i zdravstvo, stručnom poslijediplomskom specijalističkom studiju iz psihijatrije, te tečajevima stalnog usavršavnja liječnika.

Član sam Povjerenstva za lijekove KBC Zagreb, Hrvatskog psihijatrijskog društva.

Hrvatskog/svjetskog društva za biologijsku psihijatriju te Hrvatskog/svjetskog društva farmakologa,          te sam član upravnog vijeća Hrvatskog društva za zaštitu osoba s intelektualniim teškoćama.

Popis publikacija:

Radovi objavljeni u: current contents:

  1. Vuksan-Cusa B, Sagud M, Jakovljevic M, Peles AM, Jaksic M, Mihaljevic S, Zivkovic M, Mikulic SK, Jevtovic S (2012)nAssociation between C-reactive protein and homocysteine with the subcomponents of metabolic syndrome in stable patients with bipolar disorder and schizophrenia. Nord J Psychiatry, u tisku
  2. Nikolac M, Sagud M, Nedic G, Nenadic Sviglin K, Mihaljevic Peles A, Uzun S, Kozumplik O, Zivkovic M, Mustapic M, Jakovljevic M, Pavlovic M, Muck Seler D, Borovecki F, Pivac N (2012) Lack of association catechol-O-methyl transferase Val158/150 Met polymorphism and smoking in schizophrenia and alcohol dependence. Psychiatry Res, u tisku
  3. Sagud M, Nikolac M, Mihaljevic-Peles A, Nedic G, Vuksan Cusa B, Mustapic M, Jakovljevic M, Muck-Seler D, Pivac N (2012) The lack of effect of ziprasidone on platelet serotonin concentration in schizophrenic patients. Psychopharmacology, 219(4):1179-81
  1. Mück-Seler D, Sagud M, Mihaljevi-Peles A, Jakovljevi M, Pivac N (2011) Baseline lipid levels and acute treatment response to paroxetine and tianeptine in depressed women. J Clin Psychopharmacol 31(3):387-90
  2. Vuksan-Ćusa B, Jakovljević M, Sagud M, Mihaljević Peleš A, Marčinko D, Topić R, Mihaljević S, Sertić J (2011) Metabolic syndrome and serum homocysteine in patients with bipolar disorder and schizophrenia treated with second generation antipsychotics. Psychiatry Res 189(1):21-5
  3. Sagud M, Mihaljevic-Peles A, Pivac N, Jakovljevic M, Muck-Seler D. Lipid levels in female patients with affective disorders. Psychiatry Res. 2009 15;168(3):218-21
  4. Mihaljevic Peles A, Bozina N, Sagud M, Rojnic Kuzman M, Lovric M. MDR1 gene polymorphism: therapeutic response to paroxetine among patients with major depression. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Aug 1;32(6):1439-44
  5. Muck-Seler D, Sagud M, Mustapic M, Nedic G, Babic A, Mihaljevic Peles A, Jakovljevic M, Pivac N. The effect of lamotrigine on platelet monoamine oxidase type B activity in patients with bipolar depression. Prog Neuropsychopharmacol Biol Psychiatry. 2008 Jul 1;32(5):1195-1198
    1. Sagud M, Pivac N, Mueck-Šeler D, Jakovljevic M, Mihaljevic-Peles A, Korsic M (2002) Effects of sertraline on plasma cortisol, prolactin and thyroid hormones in female depressed patients. Neuropsychobiology 45 (3): 139-143
  1. Sagud M, Pivac N, Mustapic M, Nedic G, Peles AM, Kramaric M, Jakovljevic M, Muck-Seler D. The effect of lamotrigine on platelet serotonin concentration in patients with bipolar depression. Psychopharmacology (Berl). 2008 May;197(4):683-685
  2. Bozina N, Peles AM, Sagud M, Bilusic H, Jakovljevic M. Association study of paroxetine therapeutic response with SERT gene polymorphisms in patients with major depressive disorder. World J Biol Psychiatry. 2008;9(3):190-197
  3. Sagud M, Mihaljević-Peleš A, Pivac N, Jakovljevic M, Muck-Seler D. Platelet serotonin and serum lipids in psychotic mania., J Affect Disord. 2007 Jan;97(1-3):247-51
  4.  Sagud M, Mihaljević-Peleš A, Muck-Seler D, Jakovljevic M, Pivac N. Quetiapine augmentation in treatment-resistant depression: a naturalistic study. Psychopharmacology (Berl). 2006 Sep;187 (4):511-512
  5. Muck-Seler D, Pivac N, Mustapic M, Crncevic Z, Jakovljevic M, Sagud M.Platelet serotonin and plasma prolactin and cortisol in healthy, depressed and schizophrenic women., Psychiatry Res. 2004 Jul 15;127(3):217-26.
  6. Barisic I, Pivac N, Muck-Seler D, Jakovljevic M, Sagud M. Comorbid depression and platelet serotonin in hemodialysis patients.
    Nephron Clin Pract. 2004;96(1):c10-4.
  7. Pivac N, Muck-Seler D, Sagud M, Jakovljevic M, Mustapic M, Mihaljevic-Peles A. Long-term sertraline treatment and peripheral biochemical markers in female depressed patients., Prog Neuropsychopharmacol Biol Psychiatry. 2003 Aug;27(5):759-65.
  8. Muck-Seler D, Pivac N, Jakovljevic M, Sagud M, Mihaljevic-Peles A. Platelet 5-HT concentration and comorbid depression in war veterans with and without posttraumatic stress disorder. J Affect Disord. 2003 Jul;75(2):171-9.
  9. Jakovljevic M, Sagud M, Mihaljevic-Peles A. Olanzapine in the treatment-resistant, combat-related PTSD–a series of case reports. Acta Psychiatr Scand. 2003 May;107(5):394-6; discussion 396.
  10. Hotujac Lj, Sagud M (2002) Efficacy and safety of long-term risperdone treatment. Int J Psychiatry Clin Practice 6 (4): 193-197
  11. Mück-eler D, Pivac N, Sagud M, Jakovljevi M, Mihaljevic-Peles A (2002) The effects of paroxetine and tianeptine on peripheral biochemical markers in major depression. Progress in Neuropsychopharmacology & Biol Psychiatry 26(7-8):1235-1243.
  12. Mück-eler D, Pivac N, Sagud M, Jakovljevi M (2002) Platelet serotonin markers in posttraumatic stress disorder. Progress in Neuropsychopharmacology & Biol Psychiatry 26 (6): 1193-1198
  13. Sagud M, Hotujac Lj, Mihaljevic-Peles A, Jakovljevic M (2002) Gender differences in depression. Coll Antropol 26 (1): 149-157
  1. Mihaljevic-Peles A, Jakovljevic M, Mrsic M, Sagud M (2001) Trombocytopenia associated with clozapine and fluphenazine. Nord J Psychiatry 55 (6): 449-450
  2. Hotujac A, Sagud M, Hotujac Lj (2000) Drug use among Croatian students. Coll Antropol 24 (1): 61-68

Poglavlja u knjigama:

1)     Marčinko D, Pivac N, Šagud M, Mück-eler D, Mihaljević-Peleš A, Jakovljević M (2011) Biološke osnove suicidalnog ponašanja. U: D. Marčinko i sur., Med. Naklada, Zagreb 2011., str. 62-81

2)    Sagud M, Mihaljević-Peleš A (2006) Psihofarmakologija. U: Suradna i konzultativna psihijatrija, R. Gregurek i sur., Šk. knjiga, Zagreb, 2006., str. 193-225

3)    Sagud M, Mihaljević-Peleš A (2006) Ginekologija i opstetricija U: Suradna i konzultativna psihijatrija, R. Gregurek i sur., Šk. knjiga, Zagreb, 2006., 132-139

4)    Mück-eler D, Pivac N, Sagud M, Mustapić M, Jakovljevi M (2005) The effects of serotonin uptake inhibitors on platelet serotonin: From basic to clinical research. U: Trends in serotonin uptake inhibitor research: 29-53

5)    Hotujac Lj, Sagud M (2001) Resorpcija, metabolizam i eliminacija benzodiazepina. U: Jakovljevic M and Lackovic Z: Benzodiazepini u suvremenoj medicini: 72-78

6)    Hotujac Lj, Sagud M (2000) Benzodiazepini. U: Durakovic Z i sur: Klinička toksikologija., Grafos, Zagreb, 2000: 345-349

Ostali radovi:

1)     Sagud M, Mihaljević-Peleš A, Begić D, Vuksan-Ćusa B, Kramarić M, Zivković M, Jakovljević M (2011) Antipsychotics as antidepressants: what is the mechanism? Psychiatr Danub 23(3):302-7.

2)    Mihaljević-Peleš A, Sagud M, Janović MB, Mikulić SK, Jevtović S (2011) Do we need new therapeutic strategies for depression? Psychiatr Danub 23(3):300-1

3)    Mihaljević-Peles A, Sagud M, Bozina N, Zivković M, Jovanović N (2010) Pharmacogenetics and antipsychotics in the light of personalized pharmacotherapy. Psychiatr Danub 22(2):335-7.

4)    Vuksan-Cusa B, Sagud M, Jakovljević M (2010) C-reactive protein and metabolic syndrome in patients with bipolar disorder compared to patients with schizophrenia. Psychiatr Danub 22(2):275-7.

5)    Sagud M, Mück-Seler D, Mihaljević-Peles A, Vuksan-Cusa B, Zivković M, Jakovljević M, Pivac N (2010) Catechol-O-methyl transferase and schizophrenia. Psychiatria Danubina 22(2):270-4

6)    Sagud M, Mihaljević-Peles A, Mück-Seler D, Pivac N, Vuksan-Cusa B, Brataljenović T, Jakovljević M (2009) Smoking and schizophrenia. Psychiatr Danub 21(3):371-5

7)    Zivković M, Mihaljević-Peles A, Sagud M, Silić A, Mihanović M. The role of CYP2D6 and TaqI A polymorphisms in malignant neuroleptic syndrome: two case reports with three episodes. Psychiatr Danub. 2010 Mar;22(1):112-6

8)    Mihaljević-Peles A, Sagud M, Bozina N, Zivković M, Jovanović N. Pharmacogenetics and interactions of antidepressants in the treatment of co-morbid illness. Psychiatr Danub. 2009 Sep;21(3):399-400

9)    Vuksan-Cusa B, Marcinko D, Sagud M, Jakovljević M. The comorbidity of bipolar disorder and cardiovascular diseases from pharmacotherapy perspective. Psychiatr Danub. 2009 Sep;21(3):382-5

10)  Sagud M, Mihaljević-Peles A, Mück-Seler D, Pivac N, Vuksan-Cusa B, Brataljenović T, Jakovljević M. Smoking and schizophrenia. Psychiatr Danub. 2009 Sep;21(3):371-375

11)   Sagud M, Mihaljević-Peles A, Pivac N, Muck-Seler D, Simunović I, Jakovljević M. Genetics of schizophrenia in the context of integrative psychiatry. Psychiatr Danub. 2008 Sep;20(3):364-8.

12)  Mihaljević-Peles A, Sagud M, Bozina N, Zivković M. Pharamacogenetics and antidepressant treatment in integrative psychiatry perspective. Psychiatr Danub. 2008 Sep;20(3):399-401.

13)  Mihaljević-Peles A, Bozina N, Sagud M. Pharmacogenetics in modern psychiatry. Psychiatr Danub. 2007 Sep;19(3):231-3.

14)  Bozina N, Mihaljevic-Peles A, Sagud M, Jakovljevic M, Sertic J. Serotonin  transporter polymorphism in Croatian patients with major depressive disorder. Psychiatr Danub. 2006 Jun;18(1-2):83-9.

15)  Sagud M, Mihaljevic-Peles A, Jakovljevic M (2002) Selektivni inhibitori ponovne pohrane serotonina. Medicus 11(2): 165-170

16)  Mihaljević-Peleš A, Šagud M, Jakovljević M (2002) Antiepileptici kao stabilizatori raspoloženja. Medicus 11 (2): 171-175

17)  Jakovljević M, Mihaljević-Peleš A, Šagud M (2002) Prirodni lijekovi u terapiji mentalnih poremećaja. Medicus 11 (2): 263-169

18)  Šagud M, Jakovljević M, Mihaljević-Peleš A, Tomić D, Di Cesare F (1999) Agranulocytosis after addition of risperidone to clozapine treatment-a case report. Psychiatria Danubina 11 (3-4): 153-158

19)  Šagud M, Hotujac Lj (1996) Prikaz bolesnice s afonijom (neophodnost stručnog konzilija). Socijalna psihijatrija 24 (2-3): 104-107

20) Hotujac Lj, Šagud M (1995) Racionalna primjena benzodiazepina. Pharmaca 33 (1-2): 47-59

21)  Šagud M, Jakovljević M, Mihaljević-Peleš A, Medved V (1995) Pharmacokinetic opitimisation of lithium treatment. Psychiatria Danubina 3-4 (7): 169-173

22) Šagud M, Klinar I, Schönwald S, Baršić B (1994) Kliničko istraživanje podnošljivosti azitromicina u djece. Pharmaca 32 (1): 57-66

23) Baršić B, Schönwald S, Klinar I, Šagud M, Šušković T (1994) Comparison of three-day azithromycin and ten-day cefaclor in the treatment of patients with lower respiratory tract infection. Pharmaca 32: 137-146

Name: MARINA ŠAGUD

Business address:Department of Psychiatry,

UniversityHospital “Rebro”,

Kišpatićeva 12, 1000 Zagreb, Croatia

Phone: 385 1 23 88 353

Fax: 385 1 23 88 329

e-mail: marinasagud@mail.com

 

Title: MD, specialist in psychiatry

EDUCATION:

Primary school, secondary school completed in Zagreb,

1988-Graduated from the School of Medicine, University of Zagreb

1992 – completed postgraduate study of clinical pharmacology, at the School of Medicine, University of Zagreb

1993-1997-Residency in psychiatry performed at the University Hospital Center Zagreb, Department of Psychiatry

2001-2003-attended PhD program at the School of Medicine, University of Zagreb

PhD degree-April, 2007

EMPLOYMENT:

  •  Pharmaceutical company “Pliva” (dealing with the clinical trials of antimycrobial agents)
  •   Department of Psychiatry, UniversityHospital “Rebro”, Zagreb (for the last 19 years)

FIELD OF PROFESSIONAL ACTIVITIES:

A rich experience in treatment of psychotic patients with schizophrenia, schizoaffective and affective disorders, as well as with PTSD. Conducting the treatment of both in- and out-patients, working at the emergency unit. Extensively involved in clinical trials. Actively participated in numerous congresses.

FIELD OF PROFESSIONAL INTEREST:

Pharmacogenomics

Psychopharmacology